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( plated ) DAILY Serum Refill cartridge
( plated ) Skin Science 30 mL DAILY Refill Serum bottle, refill cartridge, and packaging with text that states 'DAILY Serum Refills are exclusively available for our upgraded packaging.
Video showing the DAILY Serum bottle and product.
Hands holding a value-size bottle of ( plated ) DAILY Serum, labeled '2x larger than INTENSE Serum'.
Scientific rendering of an exosome featuring the text 'Powered by Renewosome™ technology. Our platelet-derived Renewosome™ exosomes are the ultimate powerhouse, working to renew the look of your skin.'
( plated ) Skin Science DAILY Serum Refill cartridge and packaging, 30 mL / 1 fl oz
4.7
Rated 4.7 out of 5 stars
223

DAILY Serum Refill

Renewing Support for Youthful, Radiant Skin

Sale price$244.00
30 mL Refill 30 mL Bottle

Visible transformation takes time. With each use, platelet-derived exosomes help support your skin’s natural renewal, driving results that continue to build long-term. Our refillable design keeps you consistent, with $14 savings built into every bottle.

Size: 30 mL / 1 fl oz

MUST have the full-size DAILY Serum for the refill to work properly.

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol

Instructions

Apply 1–2 times daily on clean, dry skin before any other skincare. Wait 5 minutes before layering additional products. Results amplify over time with consistent use.

Awards

Oprah Daily Editor's Choice 2023
( plated ) DAILY Serum Refill cartridge
DAILY Serum Refill Sale price$244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle

Renew. Refill. Repeat.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!
Silver ( plated ) DAILY Serum bottle next to droplets of serum

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

Exosome Science in Action

Visibly Transformative Results

Before-and-after comparison of a man's face showing visible skin barrier improvement over 12 weeks.
Before and after comparison of a person's face with visible skin texture changes over 12 weeks.
Before and after comparison of a person's face, showing visible improvement over 6 weeks.

Where Biotech Meets Beauty™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

EXPLORE THE SCIENCE
4.7
Rated 4.7 out of 5 stars
Based on 223 reviews
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223 reviews
  • Robert B.
    Verified Buyer
    Rated 3 out of 5 stars
    9/11/26
    Solid performing serum

    This serum works better for me than any I have tried so it has become a staple in my daily skincare routine. The reason for the lower rating is that the delivery system has failed a few times and have to use a cotton swab to get remaining product out of the bottle.

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  • Kathleen O.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    9/10/26
    A nice option

    For every day or for younger skin this is a great option. I used as daytime serum

    Was this helpful?
  • Ellen H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/9/26
    Plated Daily Serum

    I’ve been using Plated Daily for just two weeks, and I’m already noticing a difference in my mature skin. My skin looks more hydrated, smoother, and has a healthy, refreshed glow that I wasn’t expecting to see this quickly.

    What I really like is how easy it is to incorporate into my routine. It feels good to use a product that is designed with mature skin in mind, and I’m excited to see how my skin continues to improve with consistent use. Two weeks in and I’m already impressed with the results! It's been truly a game changer!

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  • Shirley R.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/8/26
    Daily Serum Refill

    If you are looking for products to stop your age if skin young or old skin are expensive however worth the money

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  • Heggy O.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/7/26
    Plated refill

    Fabuious

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  • Sheri H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/5/26
    Love Plated!

    I love every Plated product, but I especially love that you can get refills on the serums. Less waste and save a few bucks plus great skin. Nothing has changed my skin like Plated has and it’s the one product I make sure I never run out of.

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  • Gina C.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/5/26
    Gina

    Simplifies my routine! Effective

    Was this helpful?
  • Nicole P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/4/26
    Awesome skincare!

    I absolutely love the daily serum! I have noticed a huge difference is the look and feel of my skin. My skin typically is on the dry side, but since starting this serum, my skin is well hydrated and never feels dry. My skin has a glow and this product has improved the overall texture and tone of my skin. I will definitely be keeping the daily serum part of my skincare routine!

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  • Mary J. K.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/2/26
    Daily serum

    Love the product. Have been using it about 1 1/2 years.

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  • Allie S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/1/26
    I never want to be without my Plated serum!!

    This serum is incredible - it has made my skin tone more even and calm. I never want to run out of the stuff

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DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum?

DAILY Serum is our deeply hydrating, platelet-derived exosome serum, known as the "glow" serum, powered by proprietary Renewosome® technology. This medical-grade formula infuses the skin with visible renewal for everyday radiance, applied once daily.

What does ( plated ) DAILY Serum do?

DAILY Serum deeply hydrates and infuses the skin with visible renewal to improve radiance. Clinically, it's been shown to reveal brighter skin, smooth the look of fine lines, and reduce the appearance of redness and dark spots, while helping defend against future signs of aging.

Who is ( plated ) DAILY Serum for?

DAILY Serum for anyone looking for daily anti-aging protection and a luminous glow. Its gentle, hydrating formula makes it an especially good fit for sensitive or barrier-compromised skin. As with all ( plated ) serums, your provider can help confirm it's the right match for your skin.

When should I use ( plated ) DAILY Serum?

DAILY Serum can be used either in the morning or at night as the first step in your skincare routine.

How often should I apply ( plated ) DAILY Serum?

DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1–2 times daily. Wait 5 minutes before layering any other skincare product.

Can I use ( plated ) DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) exosome serums first to clean, product-free skin. And let it sit for 5 minutes before applying other products.

The platelet-derived exosomes in our Renewosome® technology work most effectively when they have direct access to your skin. After waiting 5 minutes, feel free to layer on any other products, such as retinol, retinoids, vitamin C, moisturizer, or sunscreen. Don't forget your SPF.

Is ( plated ) DAILY Serum suitable for all skin types?

Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.

After a skin procedure such as laser, microneedling, or a chemical peel, and after using ( plated ) CALM Serum post-procedure, is ( plated ) DAILY Serum the best to transition to afterward?

You may choose to stick to CALM Serum or transition to DAILY Serum (renewing support for a youthful glow) or INTENSE Serum (maximum exosome concentration for mature or stressed skin). Your provider can help you select the best choice for your skin goals.