Frequently Asked Questions
General
We source our platelets exclusively from FDA-regulated donation banks in the United States. After the approved transfusion window has passed, select, qualified, healthy donors are carefully chosen for our process.
These platelets are gently processed to isolate their delicate exosomes, which then undergo rigorous testing to ensure exceptional purity and safety.
( plated ) Skin Science serums are developed and manufactured in our Rochester, Minnesota laboratories, where these ethically sourced, human platelet-derived exosomes are incorporated into our proprietary Renewosome® technology. This controlled process ensures high levels of purity, potency, and consistency from batch to batch.
Our products are formulated in the United States using FDA-approved platelet sources.
( plated ) products are absorbed into the skin through cells of the epidermis and through hair follicles. The molecular structure of the exosome is under 500kd, which allows for easy penetration through the skin.
Think of exosomes as tiny egg-like packages that deliver powerful benefits to your skin in the form of antioxidants and peptides (phosphopeptides to be exact!).
Our proprietary Renewosome® technology processes platelet-derived exosomes through an advanced and extremely gentle ultrafiltration that allows exosomes to keep their “shell” (aka lipid bilayer) intact. This is imperative for shelf stability.
By comparison, a process such as centrifugation places an enormous amount of pressure on the exosomes. This causes the delicate “shell” to crack, producing an unstable serum that requires refrigeration.
We recommend storing your products at room temperature. Please avoid storing any of your products at temperatures below 50°F (10°C) or above 95°F (35°C) for extended periods.
Our products are produced in small, in-house batches and are shelf-stable for up to 12 months when stored correctly. This should include keeping them out of extreme heat and cold.
Most ( plated ) Skin Science serums are designed to be used once daily as the first step after cleansing. Apply a small amount to clean, dry skin and allow the serum to fully absorb before applying additional skincare products.
Some serums may be used up to twice daily, depending on the specific product and your skincare routine. For best results, follow the instructions provided with each serum and use consistently to support visible skin renewal.
While results can vary by skin type and reason for use, most participants in clinical trials reported a positive impact after 6 weeks of use.
( plated ) is a cosmetic topical product line. At this time, it has not been FDA-approved for use in micro-needling procedures.
Our formulas do not contain many of today's most harmful and questionable ingredients. At this time, however, there is not enough clinical data to support claims of safety during pregnancy and breastfeeding. If you are pregnant or breastfeeding, we always recommend that you consult with your physician before using ( plated ) Skin Science products. A detailed ingredient list is available on our product pages.
( plated ) Skin Science does not currently operate retail store locations. Our products are available through leading medical providers and aesthetic practices, as well as directly through our website.
( plated ) Skin Science offers a dedicated B2B partnership program for qualified medical providers and aesthetic practices. To inquire about carrying ( plated ) in your practice, please apply here: https://platedskinscience.com/pages/providers.
To get in touch, please email info@platedskinscience.com or fill out the form on our Contact Us page.
FACE Serums
Both the INTENSE and DAILY Serums are breakthrough formulas that deliver next-level anti-aging results.
- INTENSE Serum (15 ml) is our most concentrated exosome formula. It was designed to address the most challenging skin concerns, such as mature skin, stubborn pigmentation, fine lines, and dullness.
- DAILY Serum (30 ml) features a slightly lower exosome concentration and a higher concentration of hydrating ingredients; consumers affectionately nicknamed it the “glow” serum. DAILY is best suited for those with moderate anti-aging, pigmentation, and tone or texture concerns. It's recommended for those looking for more gradual results or those interested in pre-juvenation and who wish to preserve, protect, and improve luminosity.
You may wish to start with INTENSE and transition to DAILY to help maintain your results. Or choose DAILY and opt for INTENSE when your skin needs an extra boost!
Retinols, Vitamin C, and our ( plated ) EYE Serum pair well with the INTENSE Serum and DAILY Serum face serums.
The carrier gel used within INTENSE Serum and DAILY Serum contains a naturally occurring substance called hyaluronic acid. This molecule, which is naturally found in the body, works to increase skin moisture and reduce the appearance of fine lines and wrinkles.
The CALM Serum is currently exclusively carried by aesthetic providers so they can help you prepare the skin for cosmetic treatments and reduce post-procedure recovery time.
If your local aesthetics provider does not offer CALM yet, please Contact Us.
INTENSE Serum
In just weeks, the clinically proven, INTENSE Serum targets the visible signs of aging with results you can see!
INTENSE Serum is our most concentrated anti-aging exosome serum, formulated specifically to improve the appearance of the most challenging skin needs, such as fine lines, wrinkles, redness, brown spots, and tone, as well as texture.
Apply INTENSE Serum 1 to 2 times per day on a dry face right after cleansing. Allow the product to dry completely (approximately 5 minutes) before layering other products.
With millions of exosomes per pump, one pump per application is all you need.
Depending on your individual skin goals and the guidance of your aesthetic provider, the recommended approach is to begin with the INTENSE Serum for 6-12 weeks to support visible renewal. After completing this initial phase, many people transition to the DAILY Serum to help maintain results and support ongoing skin maintenance.
Yes! According to a top dermatologist-researcher, ( plated ) may increase the efficiency of your other favorite skincare ingredients like vitamin C and retinol!
For best results, always apply ( plated ) serums first to clean, product-free skin. And, let it sit for 5 minutes before applying other products.
The exosomes in our Renewosome® technology work most effectively when they have direct access to your skin. Once the INTENSE Serum has dried, you'll know it has absorbed, and you can feel free to layer on any other products, such as ( plated ) EYE Serum, retinol, retinoid, vitamin C, moisturizer, sunscreen, etc.
No. Our INTENSE Serum will not cause sun sensitivity. You can apply it in the morning or at night as you wish. In fact, our exosome Renewosome® technology has been shown to help deliver advanced environmental protection against oxidative damage from UVA/UVB rays, pollution, and more.
Of course, we still recommend you use your daily SPF!
Based on the recommendation of your provider, you may choose the DAILY Serum. However, you may wish to start with the INTENSE Serum and transition to the DAILY Serum to help maintain your results. Both serums will support your results.
INTENSE Serum might be better suited for you if you are still struggling with wrinkles, fine lines, or stubborn pigmentation.
Backed by clinically proven results and recommended by top aestheticians, injectors, dermatologists, and plastic surgeons, ( plated ) delivers the most cutting-edge science and technology to your skincare routine.
The science behind ( plated ) serums was carefully researched and curated over more than 15 years to bring the power of platelet-derived exosomes, their remarkable cargo, and renewing power into a powerful serum while also being soothing and gentle.
Our serums truly have the impact and action of multiple products in one! ( plated ) offers the power of platelet-derived exosomes, antioxidants, peptides, amino acids, collagen, and hyaluronic acid (a powerhouse serum that replaces many steps).
Don't forget, a little serum (just one pump!) goes a long way. With millions of exosomes per pump, one pump per application is all you need. One bottle of INTENSE Serum contains approximately 64 pumps. That's over two months of use!
An investment, for sure. But, worth it!? Definitely! Because you're worth the investment!
DAILY Serum
Consumers affectionately nicknamed the DAILY Serum the “GLOW” serum.
DAILY Serum features a high concentration of hydrating ingredients and is formulated to help maintain visible improvements in skin tone, texture, and luminosity. Powered by proprietary Renewosome® technology, it delivers ongoing exosome support to reinforce long-term skin health.
DAILY is best suited for those with moderate anti-aging, pigmentation, and tone or texture concerns. It's recommended for those seeking more gradual results, or for those interested in pre-juvenation and who wish to preserve, protect, and improve luminosity.
Many people transition to the DAILY Serum after completing a 6-12 week course of INTENSE Serum. DAILY is designed to support continued renewal and help sustain visible results as part of an ongoing routine.
DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1-2 times daily, allowing the formula to fully absorb before layering additional skincare products.
Yes! For best results, always apply ( plated ) serums first to clean, product-free skin. And, let it sit for 5 minutes before applying other products.
The exosomes in our Renewosome® technology work most effectively with direct access to your skin. Once the DAILY Serum has dried, you'll know it has absorbed, and you can feel free to layer on any other products such as retinol, retinoid, vitamin C, moisturizer, sunscreen, etc. Don't forget your SPF!
Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.
Based on the recommendation of your provider, you may choose DAILY. However, you may wish to start with the INTENSE Serum and transition to the DAILY Serum to help maintain your results. Both serums will support your results.
INTENSE Serum might be better suited for you if you are still struggling with wrinkles, fine lines, or stubborn pigmentation.
EYE Serum
The ( plated ) EYE and INTENSE Serums both harness the breakthrough power of platelet-derived exosomes to visibly renew and refresh the look of skin. In fact, the exosome concentration in both products is the same, and both are clinically proven to reduce the appearance of fine lines, wrinkles, texture, and discoloration.
The formulations differ in the supporting science-backed ingredients. EYE Serum contains actives, including dual-seaweed extract and coffee arabica extract, that are known to be especially beneficial for the very thin skin around the eyes.
The EYE Serum works best when used consistently:
- Apply daily as the first step in your skincare routine.
- Dispense by pressing the green button, then glide the metal applicator around your eye. One pump for both eyes.
- Wait 5 minutes before layering with other products.
You may notice immediate improvement to the look of under puffiness, wrinkles, and dark circles thanks to the hyaluronic acid and coffee arabica extract, which can provide nearly instant visible effects.
Our platelet-derived exosomes work on a deeper level to reprogram the look of aging skin. In our consumer study, participants began to show visible results in as little as four weeks using the ( plated ) EYE Serum.
If you use the recommended one pump per day, the EYE Serum is designed to last approximately 2.5 months. This may differ depending on how often and how much of the serum you apply.
Yes, please do!
The EYE Serum is safe and effective for the entire eye area, above and below, 360° around the eye, right up to the lash line.
Yes, the EYE Serum is formulated to be safe for all skin types, including sensitive skin. In our consumer study, there were zero reports of adverse effects.
HAIR Serum
( plated ) HAIR Serum is a groundbreaking scientific achievement in hair and scalp care, the first platelet-derived exosome technology designed to deliver powerful nutrients to the scalp.
The proprietary blend of platelet-derived exosomes found in Renewosome® technology are formulated into a serum clinically proven to help make hair look fuller, stronger, and thicker.
The platelet-derived exosomes in the HAIR Serum support the scalp by delivering a growth factor complex and powerful antioxidants to the skin, setting the stage for your hair to look and act at its absolute best.
The key ingredient in the HAIR Serum is the proprietary blend of platelet-derived exosomes found in Renewosome® technology, which work to strengthen the body's ability to support stronger-looking and feeling hair.
A 9-month clinical study is currently in progress for the HAIR Serum, building on the promising results we saw during the 6-month trial. Stay tuned for what's to come!
The HAIR Serum is ideal for individuals experiencing hair-related concerns such as thinning hair, shedding, lack of volume, or those seeking to improve their hair's overall health and appearance.
Our initial studies show that the platelet-derived exosomes in the HAIR Serum can aid in helping the body set the stage for strong, healthy-looking hair. The proprietary blend of platelet-derived exosomes delivered via our Renewosome® technology can act like fertilizer for the scalp, delivering key growth factors and nutrients to help fill in the gaps.
By using the HAIR Serum, you should start noticing improvements in the appearance of your hair, including density, strand thickness, shine, moisture, reduced breakage, and overall healthier-looking hair within weeks.
- Consistency is key to seeing results as quickly as possible, and full results typically develop over 3-6 months with continued use.
With regular use, the HAIR Serum helps maintain its benefits, making hair appear fuller, stronger, and thicker.
Yes, continued use of the HAIR Serum is recommended to maintain your hair's appearance. Regular application can help sustain the benefits and improvements over the long term.
Platelet-derived exosomes support the scalp by delivering a growth factor complex and powerful antioxidants to the skin, setting the stage for your hair to look and act at its absolute best.
Apply once daily to a clean, dry scalp. Dispense 1–2 pre-filled droppers directly to areas of concern and gently massage into the scalp. The formula is lightweight and non-greasy, designed for effortless layering. Allow 5 minutes for full absorption before applying additional products or using heat styling tools.
You can apply the product to either wet or dry hair, making it versatile for your needs. For the best results, it's recommended to wait at least 1 hour after application before heat styling, washing your hair, or using other hair products. This ensures optimal absorption and effectiveness.
The HAIR Serum is formulated by combining Renewosome® technology with an innovative blend of nurturing ingredients designed to support and boost the scalp and increase the appearance of hair's density, thickness, volume, and overall appearance. Check out the detailed ingredient list here:
- Renewosome® technology is our proprietary blend of platelet-derived exosomes, containing growth factor complex, and potent antioxidants.
- Our innovative antioxidant blend helps reduce the appearance of hair and scalp damage due to emotional stress, sun exposure, and environmental pollutants.
- Biotin inspires stronger-looking hair (by encouraging keratin synthesis).
- Sea Moss fortifies hair follicles.
- Hyaluronic Acid conditions and hydrates your scalp.
- Turmeric provides skin-calming properties.
- Lindera Strychnifolia Root Extract primes the skin on your scalp.
The HAIR Serum is designed for at-home use, without the need for microneedling or needles of any kind. If you are receiving microneedling or PRP through a healthcare provider, we recommend you speak with them about post-procedure care instructions.
Yes, our HAIR Serum is formulated to be beneficial for all hair types.
- Each bottle if HAIR Serum contains 90 pre-measured dropperfuls, enough for a 3-month supply when using one dropper per day.
- Depending on the size of the area you're targeting, you may need more than one dropper per day; in that case, the bottle may last approximately 2 months.
- The dropper is intentionally pre-loaded to about half full as you unscrew the cap; there's no need to pull up more. That's plenty of product to spread across several targeted areas.
- For optimal results, apply directly to the scalp rather than the hair, as this promotes easier distribution and improved absorption.
The HAIR Serum is not specifically formulated to stimulate facial hair growth, but we continually explore new potential uses and benefits of our Renewosome® technology.
The HAIR Serum is formulated to support fuller, healthier-looking hair by improving the appearance of density, strand thickness, shine, moisture, and overall hair vitality.
While the formula is designed to enhance the overall look and health of your hair, it was not developed to address hair discoloration or reverse grey hair.
- Our HAIR Serum is the first platelet-derived exosome technology designed to deliver a powerful growth factor complex and nutrients to the scalp. The serum works like a fertilizer by priming the scalp, creating an ideal environment and providing the essential antioxidants necessary for thicker-looking hair. This innovative approach targets hair challenges at a cellular level, unlike many other products that focus on superficial treatment.
- ( plated ) HAIR Serum is the first-time patients have been able to use platelet-derived exosomes at home for hair. There are a few botanical exosome serum products on the market for hair, but we know the source of exosomes is the most critical element. Our Renewosome® technology is a patented process that ensures only ( plated ) offers platelet-derived exosomes in our at-home, prescription-free products.
- The technology found in our skincare serums and increases the concentration of platelet-derived exosomes to the highest concentration of any of our products. We then combine that with natural ingredients that can help to further reduce the appearance of hair and scalp damage.
CALM Serum
( plated ) CALM Serum can be applied 2-3 times a day after an ablative or non-ablative procedure to help decrease recovery time and enhance the results of the procedure.
As a cosmetic, the CALM Serum is classified only for use on intact skin. During the initial phases of clinical trials, CALM was applied immediately after CO2. However, you may choose to initiate the CALM application on the day after any laser procedure.
Most patients transition to the DAILY Serum after the CALM Serum. The DAILY Serum will help maintain the results you have achieved and add additional hydration, luminosity, and glow to your skin.
The CALM Serum is designed as a post-procedure product with added ingredients to enhance hydration, soothe the skin, and improve tolerability post-procedure.
Patients using ( plated ) CALM Serum demonstrated significant improvement within 5 days of being post-procedure.
An Ultra Pulse CO2 laser was used in the study at the following settings: Energy: 125 mJ, Density: 3, 10 HZ, Size: 5-7, Pattern: 1
Shipping & Returns
It takes us 2-3 business days to process your order. Once processing is complete, we will ship your order to you within 5-7 business days. A notification email will be sent to you on the day your product is shipped. For additional details, please view our shipping policy.
We're happy to offer free standard shipping within the U.S.!
At this time, ( plated ) Skin Science does not offer expedited shipping options. Orders are shipped via our standard delivery service.
At this time, orders placed on our website only ship within the United States. We look forward to expanding to international destinations in the future.



