Exosome Serum Refills

We source our platelets exclusively from FDA-regulated donation banks in the United States. After the approved transfusion window has passed, select, qualified, healthy donors are carefully chosen for our process.

These platelets are gently processed to isolate their delicate exosomes, which then undergo rigorous testing to ensure exceptional purity and safety.

( plated ) Skin Science serums are developed and manufactured in our Rochester, Minnesota laboratories, where these ethically sourced, human platelet-derived exosomes are incorporated into our proprietary Renewosome® Technology. This controlled process ensures high levels of purity, potency, and consistency from batch to batch.

Our products are formulated in the United States using FDA-approved platelet sources.

( plated ) products are absorbed into the skin through cells of the epidermis and through hair follicles. The molecular structure of the exosome is under 500kd, which allows for easy penetration through the skin.

Think of exosomes as tiny egg-like packages that deliver powerful benefits to your skin in the form of antioxidants and peptides (phosphopeptides to be exact!).

Our proprietary Renewosome® Technology processes platelet-derived exosomes through an advanced and extremely gentle ultrafiltration that allows exosomes to keep their “shell” (aka lipid bilayer) intact. This is imperative for shelf stability.

By comparison, a process such as centrifugation places an enormous amount of pressure on the exosomes. This causes the delicate “shell” to crack, producing an unstable serum that requires refrigeration.

We recommend storing your products at room temperature. Please avoid storing any of your products at temperatures below 50°F (10°C) or above 95°F (35°C) for extended periods.

Our products are produced in small, in-house batches and are shelf-stable for up to 12 months when stored correctly. This should include keeping them out of extreme heat and cold.

While results can vary by skin type and reason for use, most participants in clinical trials reported a positive impact after 6 weeks of use.

In just weeks, the clinically proven, INTENSE Serum targets the visible signs of aging with results you can see!

INTENSE Serum is our most concentrated anti-aging exosome serum, formulated specifically to improve the appearance of the most challenging skin needs, such as fine lines, wrinkles, redness, brown spots, and tone, as well as texture.

Apply INTENSE Serum 1 to 2 times per day on a dry face right after cleansing. Allow the product to dry completely (approximately 5 minutes) before layering other products.

With millions of exosomes per pump, one pump per application is all you need.

Depending on your individual skin goals and the guidance of your aesthetic provider, the recommended approach is to begin with the INTENSE Serum for 6-12 weeks to support visible renewal. After completing this initial phase, many people transition to the DAILY Serum to help maintain results and support ongoing skin maintenance.

Yes! According to a top dermatologist-researcher, ( plated ) may increase the efficiency of your other favorite skincare ingredients like vitamin C and retinol!

For best results, always apply ( plated ) serums first to clean, product-free skin. And, let it sit for 5 minutes before applying other products.

The exosomes in our Renewosome® Technology work most effectively when they have direct access to your skin. Once the INTENSE Serum has dried, you'll know it has absorbed, and you can feel free to layer on any other products, such as ( plated ) EYE Serum, retinol, retinoid, vitamin C, moisturizer, sunscreen, etc.

No. Our INTENSE Serum will not cause sun sensitivity. You can apply it in the morning or at night as you wish. In fact, our exosome Renewosome® Technology has been shown to help deliver advanced environmental protection against oxidative damage from UVA/UVB rays, pollution, and more.

Of course, we still recommend you use your daily SPF!

Consumers affectionately nicknamed the DAILY Serum the “GLOW” serum.

DAILY Serum features a high concentration of hydrating ingredients and is formulated to help maintain visible improvements in skin tone, texture, and luminosity. Powered by proprietary Renewosome® Technology, it delivers ongoing exosome support to reinforce long-term skin health.

DAILY is best suited for those with moderate anti-aging, pigmentation, and tone or texture concerns. It's recommended for those seeking more gradual results, or for those interested in pre-juvenation and who wish to preserve, protect, and improve luminosity.

Many people transition to the DAILY Serum after completing a 6-12 week course of INTENSE Serum. DAILY is designed to support continued renewal and help sustain visible results as part of an ongoing routine.

DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1-2 times daily, allowing the formula to fully absorb before layering additional skincare products.

Yes! For best results, always apply ( plated ) serums first to clean, product-free skin. And, let it sit for 5 minutes before applying other products.

The exosomes in our Renewosome® Technology work most effectively with direct access to your skin. Once the DAILY Serum has dried, you'll know it has absorbed, and you can feel free to layer on any other products such as retinol, retinoid, vitamin C, moisturizer, sunscreen, etc. Don't forget your SPF!

Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.