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( plated ) DAILY Serum Refill cartridge
( plated ) Skin Science 30 mL DAILY Refill Serum bottle, refill cartridge, and packaging with text that states 'DAILY Serum Refills are exclusively available for our upgraded packaging.
Video showing the DAILY Serum bottle and product.
Hands holding a value-size bottle of ( plated ) DAILY Serum, labeled '2x larger than INTENSE Serum'.
Scientific rendering of an exosome featuring the text 'Powered by Renewosome™ technology. Our platelet-derived Renewosome™ exosomes are the ultimate powerhouse, working to renew the look of your skin.'
( plated ) Skin Science DAILY Serum Refill cartridge and packaging, 30 mL / 1 fl oz
4.7
Rated 4.7 out of 5 stars
195

DAILY Serum Refill

Renewing Support for Youthful, Radiant Skin

Sale price$244.00
30 mL Refill 30 mL Bottle

Visible transformation takes time. With each use, platelet-derived exosomes help support your skin’s natural renewal, driving results that continue to build long-term. Our refillable design keeps you consistent, with $14 savings built into every bottle.

Size: 30 mL / 1 fl oz

MUST have the full-size DAILY Serum for the refill to work properly.

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol

Instructions

Apply 1–2 times daily on clean, dry skin before any other skincare. Wait 5 minutes before layering additional products. Results amplify over time with consistent use.

Awards

Oprah Daily Editor's Choice 2023
( plated ) DAILY Serum Refill cartridge
DAILY Serum Refill Sale price$244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle

Renew. Refill. Repeat.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!
Silver ( plated ) DAILY Serum bottle next to droplets of serum

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

Exosome Science in Action

Visibly Transformative Results

Before-and-after comparison of a man's face showing visible skin barrier improvement over 12 weeks.
Before and after comparison of a person's face with visible skin texture changes over 12 weeks.
Before and after comparison of a person's face, showing visible improvement over 6 weeks.

Where Biotech Meets Beauty™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

EXPLORE THE SCIENCE
4.7
Rated 4.7 out of 5 stars
Based on 195 reviews
Total 5 star reviews: 154
Total 4 star reviews: 29
Total 3 star reviews: 4
Total 2 star reviews: 2
Total 1 star reviews: 6
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195 reviews
  • Manya S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/13/26
    Clean Plate-d

    We should have a Michelin starred "Clean plated club." When a serum is this exquisite, (and effective) you use every last drop and immediately order seconds. Love it. In my 60s and I look fantastic! Thank you, Plated!

    Was this helpful?
  • MARY H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/8/26
    All plated products

    I have been using Plated products for over a year. I live the results and will not try any other products

    Was this helpful?
  • Jean L.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/8/26
    Daily Serum

    Love the Daily Serum. I put it on every morning after I wash my face let it sit for about 5 minutes and then apply my tinted sun screen.

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  • Linda L.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/8/26
    Love this daily serum

    I first heard about the plated serums from my daughter. It was recommended to her by her dermatologist. I started with the Intense serum which I used for 3 months and noticed how smooth my skin felt and my dark spots were noticeably lighter. The redness on my nose has also faded. I most recently purchased the daily serum. It goes on smoothly and feels nice on my face. My skin continues to feel smooth and I’m most happy that the browns spots have faded. I’m in my 70’s and wish that I had known about Plated years ago. Regardless I feel like I am taking care of my skin and it’s so nice to see changes when I look in the mirror. Very happy and I would recommend Intense and the daily serum no matter what your age.

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  • Cathy W.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/7/26
    Great Product!

    I alternate monthly the daily and intense serum. My skin has never looked better.

    Was this helpful?
  • Krishma Z.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    8/7/26
    Great product!

    This product was recommended by my dermatologist and it has become a sincere strains in my routine.

    Was this helpful?
  • Barbara N. S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/7/26
    Waiting for Results

    Thanks to Plated my skin feels smooth but firm. I'm waiting for something more dramatic, but am pleased with what I see so far.

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  • Ingrid M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/7/26
    Worth every penny!

    My dermatologist recommended this to me and assured me that the investment in my skin would be noticeable within days. She was right! My 60 year old skin drank the serum up. I’m on my second bottle. I don’t waste my money on another creams or serums.

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  • christina f.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/6/26
    Fantastic

    I love all the Plated products. Nothing like them on the market. I’m a physician and only use products backed by science.

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  • Erika P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/6/26
    Maintenance: ✔️

    This serum is much lighter than the Intense, but it great for maintenance results. I have noticed a greater glow, oil balance, minimized pore side, and reduction in overall discoloration since using.

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DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum?

DAILY Serum is our deeply hydrating, platelet-derived exosome serum, known as the "glow" serum, powered by proprietary Renewosome® technology. This medical-grade formula infuses the skin with visible renewal for everyday radiance, applied once daily.

What does ( plated ) DAILY Serum do?

DAILY Serum deeply hydrates and infuses the skin with visible renewal to improve radiance. Clinically, it's been shown to reveal brighter skin, smooth the look of fine lines, and reduce the appearance of redness and dark spots, while helping defend against future signs of aging.

Who is ( plated ) DAILY Serum for?

DAILY Serum for anyone looking for daily anti-aging protection and a luminous glow. Its gentle, hydrating formula makes it an especially good fit for sensitive or barrier-compromised skin. As with all ( plated ) serums, your provider can help confirm it's the right match for your skin.

When should I use ( plated ) DAILY Serum?

DAILY Serum can be used either in the morning or at night as the first step in your skincare routine.

How often should I apply ( plated ) DAILY Serum?

DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1–2 times daily. Wait 5 minutes before layering any other skincare product.

Can I use ( plated ) DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) exosome serums first to clean, product-free skin. And let it sit for 5 minutes before applying other products.

The platelet-derived exosomes in our Renewosome® technology work most effectively when they have direct access to your skin. After waiting 5 minutes, feel free to layer on any other products, such as retinol, retinoids, vitamin C, moisturizer, or sunscreen. Don't forget your SPF.

Is ( plated ) DAILY Serum suitable for all skin types?

Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.

After a skin procedure such as laser, microneedling, or a chemical peel, and after using ( plated ) CALM Serum post-procedure, is ( plated ) DAILY Serum the best to transition to afterward?

You may choose to stick to CALM Serum or transition to DAILY Serum (renewing support for a youthful glow) or INTENSE Serum (maximum exosome concentration for mature or stressed skin). Your provider can help you select the best choice for your skin goals.