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( plated ) DAILY Serum Refill cartridge
( plated ) Skin Science 30 mL DAILY Refill Serum bottle, refill cartridge, and packaging with text that states 'DAILY Serum Refills are exclusively available for our upgraded packaging.
Video showing the DAILY Serum bottle and product.
Hands holding a value-size bottle of ( plated ) DAILY Serum, labeled '2x larger than INTENSE Serum'.
Scientific rendering of an exosome featuring the text 'Powered by Renewosome™ technology. Our platelet-derived Renewosome™ exosomes are the ultimate powerhouse, working to renew the look of your skin.'
( plated ) Skin Science DAILY Serum Refill cartridge and packaging, 30 mL / 1 fl oz
4.7
Rated 4.7 out of 5 stars
4.7 out of 5 Stars (258 Reviews)

Renewing Support for Youthful, Radiant Skin

DAILY Serum Refill

Sale price $244.00
30 mL Refill 30 mL Bottle

Visible transformation takes time. With each use, platelet-derived exosomes support your skin's natural renewal, driving results that build over time. Our refillable design helps you stay consistent, with $14 in savings built into every bottle.

MUST have the full-size DAILY Serum for the refill to work properly.

Size

30mL / 1 fl oz

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol

Instructions

Once or twice daily, begin your skincare routine with a gentle cleanser. Then, if desired, sweep a ( plated ) pad across your face and neck. Do not rinse.

Follow immediately with your ( plated ) serum. Allow 5 minutes before layering other products. With consistent use, results amplify over time.

Awards

Oprah Daily Editor's Choice 2023
( plated ) DAILY Serum Refill cartridge
DAILY Serum Refill Sale price $244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle

Renew. Refill. Repeat.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!
Silver ( plated ) DAILY Serum bottle next to droplets of serum

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

Exosomes in Action

Visibly Transformative Results

Skin Appears Visibly Calmer

Before

Before

At 12 Weeks

At 12 Weeks

Visibly Improved Skin Clarity

Before

Before

At 12 Weeks

At 12 Weeks

More Even-Looking Skin Tone

Before

Before

At 12 Weeks

At 12 Weeks

Where Biotech Meets Beauty™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

EXPLORE THE SCIENCE

See What They're saying

Customer Reviews

4.7
Rated 4.7 out of 5 stars
Based on 258 reviews
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258 reviews
  • Olivia S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/12/26
    Love!

    Love this product!

    Was this helpful?
  • Lia T.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/12/26
    Excellent product

    I’ve been using plated for a couple of years. I began with the intense and only just switched to the daily which I think is great for maintenance. Both are fantastic and will be part of my skincare routine for a long time.

    Was this helpful?
  • Julie E.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/11/26
    Love this stuff

    Truly wonderful result, skin is smooth and supple. No irritation on my sensitive skin, and my face looks healthier than it ever has.

    Was this helpful?
  • Holly M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/11/26
    Worth it!

    Skin texture has greatly improved. Reduced pore size, more even skin tone. Believer!

    Was this helpful?
  • Natalia G. U.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/10/26
    Fantastic!

    This is a fantastic product! I started with Intensive serum and then moved to Daily serum. My skin has visibly improved. Wrinkles and discolorations are less visible. Skin is moisturized and plump. I highly recommend it, it’s worth it’s price.

    Was this helpful?
  • Rachel C.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/9/26
    Great Serum !

    I absolutely love this Serum! It feels amazing and really works .

    Was this helpful?
  • Meredith V.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/8/26
    Fountain of Youth

    best serum ever

    Was this helpful?
  • Amie P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/5/26
    Awesome!

    3 refills later, totally hooked. Love the way my skin looks.

    Was this helpful?
  • Victoria H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/5/26
    Daily Serum

    I absolutely love this serum! I have now been using it for about a year, and I have noticed a significant different from when I wouldn’t not use it before. It has helped calm down my redness and I also love to use it post treatment when I can’t use any actives, but still want that hydration. My skin has done a 180!

    Was this helpful?
  • Jennifer M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/4/26
    Amazing!

    I can definitely see an improvement in my skin with consistent use!!

    Was this helpful?
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DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum?

DAILY Serum is our deeply hydrating, platelet-derived exosome serum, known as the "glow" serum, powered by proprietary Renewosome® technology. This medical-grade formula infuses the skin with visible renewal for everyday radiance, applied once daily.

What does ( plated ) DAILY Serum do?

DAILY Serum deeply hydrates and infuses the skin with visible renewal to improve radiance. Clinically, it's been shown to reveal brighter skin, smooth the look of fine lines, and reduce the appearance of redness and dark spots, while helping defend against future signs of aging.

Who is ( plated ) DAILY Serum for?

DAILY Serum for anyone looking for daily anti-aging protection and a luminous glow. Its gentle, hydrating formula makes it an especially good fit for sensitive or barrier-compromised skin. As with all ( plated ) serums, your provider can help confirm it's the right match for your skin.

When should I use ( plated ) DAILY Serum?

DAILY Serum can be used in the morning and at night as the first step in your skincare routine.

How often should I apply ( plated ) DAILY Serum?

Once or twice daily, begin your skincare routine with a gentle cleanser. Then, if desired, sweep a ( plated ) pad across your face and neck. Do not rinse. Follow immediately with your ( plated ) serum. Allow 5 minutes before layering other products. With consistent use, results amplify over time.

Can I use ( plated ) DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) exosome serums first to clean, product-free skin.

Begin your skincare routine with a gentle cleanser. Then, if desired, sweep a ( plated ) pad across your face and neck. Do not rinse. Follow immediately with your ( plated ) serum. Allow 5 minutes before layering other products.

The platelet-derived exosomes in our Renewosome® technology work most effectively when they have direct access to your skin. After waiting 5 minutes, feel free to layer on any other products, such as retinol, retinoids, vitamin C, moisturizer, or sunscreen. Don't forget your SPF.

Is ( plated ) DAILY Serum suitable for all skin types?

Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.

After a skin procedure such as laser, microneedling, or a chemical peel, and after using ( plated ) CALM Serum post-procedure, is ( plated ) DAILY Serum the best to transition to afterward?

You may choose to stick to CALM Serum or transition to DAILY Serum (renewing support for a youthful glow) or INTENSE Serum (maximum exosome concentration for mature or stressed skin). Your provider can help you select the best choice for your skin goals.