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( plated ) DAILY Serum Refill cartridge
( plated ) Skin Science 30 mL DAILY Refill Serum bottle, refill cartridge, and packaging with text that states 'DAILY Serum Refills are exclusively available for our upgraded packaging.
Video showing the DAILY Serum bottle and product.
Hands holding a value-size bottle of ( plated ) DAILY Serum, labeled '2x larger than INTENSE Serum'.
Scientific rendering of an exosome featuring the text 'Powered by Renewosome™ technology. Our platelet-derived Renewosome™ exosomes are the ultimate powerhouse, working to renew the look of your skin.'
( plated ) Skin Science DAILY Serum Refill cartridge and packaging, 30 mL / 1 fl oz
4.7
Rated 4.7 out of 5 stars
215

DAILY Serum Refill

Renewing Support for Youthful, Radiant Skin

Sale price$244.00
30 mL Refill 30 mL Bottle

Visible transformation takes time. With each use, platelet-derived exosomes help support your skin’s natural renewal, driving results that continue to build long-term. Our refillable design keeps you consistent, with $14 savings built into every bottle.

Size: 30 mL / 1 fl oz

MUST have the full-size DAILY Serum for the refill to work properly.

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol

Instructions

Apply 1–2 times daily on clean, dry skin before any other skincare. Wait 5 minutes before layering additional products. Results amplify over time with consistent use.

Awards

Oprah Daily Editor's Choice 2023
( plated ) DAILY Serum Refill cartridge
DAILY Serum Refill Sale price$244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle

Renew. Refill. Repeat.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!
Silver ( plated ) DAILY Serum bottle next to droplets of serum

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

Exosome Science in Action

Visibly Transformative Results

Before-and-after comparison of a man's face showing visible skin barrier improvement over 12 weeks.
Before and after comparison of a person's face with visible skin texture changes over 12 weeks.
Before and after comparison of a person's face, showing visible improvement over 6 weeks.

Where Biotech Meets Beauty™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

EXPLORE THE SCIENCE
4.7
Rated 4.7 out of 5 stars
Based on 215 reviews
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215 reviews
  • Mary J. K.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/2/26
    Daily serum

    Love the product. Have been using it about 1 1/2 years.

    Was this helpful?
  • Allie S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/1/26
    I never want to be without my Plated serum!!

    This serum is incredible - it has made my skin tone more even and calm. I never want to run out of the stuff

    Was this helpful?
  • Barbara N. S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/31/26
    Remains to be seen

    Now on my 3rd bottle of Plated. Waiting to see if it changes the appearance of my skin.

    Was this helpful?
  • Brad M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/30/26
    Month three and improving

    I’m seeing a noticeable difference in my third month of using the daily. Very happy with the results so far.

    Was this helpful?
  • Paige S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/29/26
    Worth it!

    I am addicted to this serum. My skin has never looked so good!

    Was this helpful?
  • Julie H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/29/26
    A product that works!

    I’ve struggled with acne and uneven, dull-looking skin for years and have tried so many different products without seeing much of a difference. Since incorporating the (plated) Daily Serum into my routine, I’ve noticed a real change in my skin. My acne has significantly improved, and my skin looks clearer, brighter, and healthier overall. It’s honestly refreshing to finally find a product that actually works for me after years of trying different things. I’m so happy with the results!

    Was this helpful?
  • Liz F.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/29/26
    Makes a BIG difference on aging skin!

    This serum has made such a difference in my skin. I thought when I turned 66 yrs old I would just have to deal with my dull, blotchy skin but this product has changed that. I hesitated for a long time buying this serum due to the expense but my esthetician finally convinced me to try and it has made a BIG difference. My skin is glowing and spots have faded. My face also looks more full. I use the eye serum also and that has reduced my dark circles and puffiness. I have cut back on my other skin products and invested in this serum. The bottle does last more than 3+ months using once a day. A little goes a long way. So happy I found this product.

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  • mirjana i.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/27/26
    my experience with Plated

    My face is smoother , little bit brighter and wrinkles are less visible.That is a lot considering my age.I use one intense plated and than 2 bottles daily plated.Also eye plated is very effective.Under eye skin is brighter and puffiness is less.

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  • Amanda M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/21/26
    Amazing brightening serum

    I love this serum, it makes my skin glow. I’ve tried other stem cell products but this one works the best!

    Was this helpful?
  • Kimberly P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/21/26
    Review

    Wonderful

    Was this helpful?
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DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum?

DAILY Serum is our deeply hydrating, platelet-derived exosome serum, known as the "glow" serum, powered by proprietary Renewosome® technology. This medical-grade formula infuses the skin with visible renewal for everyday radiance, applied once daily.

What does ( plated ) DAILY Serum do?

DAILY Serum deeply hydrates and infuses the skin with visible renewal to improve radiance. Clinically, it's been shown to reveal brighter skin, smooth the look of fine lines, and reduce the appearance of redness and dark spots, while helping defend against future signs of aging.

Who is ( plated ) DAILY Serum for?

DAILY Serum for anyone looking for daily anti-aging protection and a luminous glow. Its gentle, hydrating formula makes it an especially good fit for sensitive or barrier-compromised skin. As with all ( plated ) serums, your provider can help confirm it's the right match for your skin.

When should I use ( plated ) DAILY Serum?

DAILY Serum can be used either in the morning or at night as the first step in your skincare routine.

How often should I apply ( plated ) DAILY Serum?

DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1–2 times daily. Wait 5 minutes before layering any other skincare product.

Can I use ( plated ) DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) exosome serums first to clean, product-free skin. And let it sit for 5 minutes before applying other products.

The platelet-derived exosomes in our Renewosome® technology work most effectively when they have direct access to your skin. After waiting 5 minutes, feel free to layer on any other products, such as retinol, retinoids, vitamin C, moisturizer, or sunscreen. Don't forget your SPF.

Is ( plated ) DAILY Serum suitable for all skin types?

Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.

After a skin procedure such as laser, microneedling, or a chemical peel, and after using ( plated ) CALM Serum post-procedure, is ( plated ) DAILY Serum the best to transition to afterward?

You may choose to stick to CALM Serum or transition to DAILY Serum (renewing support for a youthful glow) or INTENSE Serum (maximum exosome concentration for mature or stressed skin). Your provider can help you select the best choice for your skin goals.