Login

Cart

Your cart is empty
DAILY Serum 30 mL full-size refill cartridge on a white background.
( plated )® Skin Science 30 mL DAILY Refill Serum bottle, refill cartidge, and packaging on a white background with text that states refills fit the latest version of the DAILY bottle.
Video showing the DAILY Serum bottle and product.
Hand holding a ( plated )® Skin Science 30 mL DAILY Refill Serum bottle labeled 'plated' with text about size and technology.
Scientific rendering of an exosome on a beige background, featuring text about Renewosome™ technology.
( plated )® Skin Science 30 mL DAILY Refill Serum cartridge and packaging on a white background.
4.6
Rated 4.6 out of 5 stars
4.6

DAILY Serum Refill

Renewing Support for Youthful, Radiant Skin

Sale price$244.00
30 mL Refill 30 mL Bottle

Visible transformation takes time. With each use, platelet-derived exosomes help support your skin’s natural renewal, driving results that continue to build long-term. Our refillable design keeps you consistent, with $14 savings built into every bottle.

Size: 30 mL / 1 fl oz

MUST have the full-size DAILY Serum for the refill to work properly.

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol
Instructions

Apply 1–2 times daily on clean, dry skin before any other skincare. Wait 5 minutes before layering additional products. Results amplify over time with consistent use.
Awards

Oprah Daily Editor's Choice 2023
DAILY Serum 30 mL full-size refill cartridge on a white background.
DAILY Serum Refill Sale price$244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle a light background

Renew. Refill. Repeat.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!
Silver ( plated ) DAILY Serum bottle on a beige background with droplets of serum.

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

Exosome Science in Action

Visibly Transformative Results

Before-and-after comparison of a man's face showing visible skin barrier improvement over 12 weeks.
Before and after comparison of a person's face with visible skin texture changes over 12 weeks.
Before and after comparison of a person's face, showing visible improvement over 6 weeks.

Where Biotech Meets Beauty™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

EXPLORE THE SCIENCE
4.6
Rated 4.6 out of 5 stars
Based on 153 reviews
Total 5 star reviews: 116 Total 4 star reviews: 26 Total 3 star reviews: 4 Total 2 star reviews: 2 Total 1 star reviews: 5
Slide 1 selected
Write a Review (Opens in a new window)
153 reviews
  • Andrea H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/1/26
    Repeat customer

    Exceptional results with steady use. Skin looks smooth and nourished. I often am asked what I do to get these results. This is the future of skincare and I am glad we have these tools in the present!

    Was this helpful?
  • Angel M. C.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    6/27/26
    Amazing

    This product does what it promises. My face and neck have decreased wrinkles. My skin feels soft and moisturized. I definitely do not look 68. I get compliments on my beautiful skin consistently.

    Was this helpful?
  • christina f.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    6/25/26
    Even better

    I initially was using only the intense serum. I bought this and was pleasantly surprised at the difference in texture which is great for daytime!

    Was this helpful?
  • Kacee S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    6/25/26
    Skin is so smooth!

    I bought the intense serum at my Dr’s office and then ordered the Daily to try it as I saw the size was bigger. I can’t believe how soft my skin is. And it’s cleared up some redness on my cheeks. Definitely part of my routine moving forward

    Was this helpful?
  • Shakira B.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    6/25/26
    Amazing

    A must buy

    Was this helpful?
  • Jason K.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    6/25/26
    Tis the goat….but…..

    I absolutely love this product and it has completely changed my skin for the better. I switched over about two years ago from TNS, and never looked back. I just wish they would have some sort of loyalty/rewards program. In this economy, with other excosome products coming onto the market, like Musy etc…. I’m not sure if I will switch over or not.

    Was this helpful?
  • Alicia S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    6/25/26
    Incredible post treatment

    I recently had a BBL Heroic and Moxi treatment for my sun spots on my chest, arms and lower legs. I used Plated Daily along with Alastin Restorative on top and my healing was much faster than expected. I could literally see the difference every day. It's an expensive recovery treatment but I wanted my investment to have great results.

    Was this helpful?
  • EstherYork
    I recommend this product
    Rated 5 out of 5 stars
    6/7/26
    5 Stars

    It makes my skin just glow!!!

    Was this helpful?
  • Sandra
    I recommend this product
    Rated 5 out of 5 stars
    5/29/26
    5 Stars

    Pricey but so worth it. 57 year old.

    Was this helpful?
  • Lauri B.
    Flag of United States
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    5/18/26
    5 Stars

    I have noticed a difference in my skin; I plan to continue to use this product. This has helped more than any other product I have used for lines & wrinkles.

    Was this helpful?
Show More

DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum designed to do?

Consumers affectionately nicknamed the ( plated ) DAILY Serum the “GLOW” serum.

DAILY Serum features a high concentration of hydrating ingredients and is formulated to help maintain visible improvements in skin tone, texture, and luminosity. Powered by proprietary Renewosome® technology, it delivers ongoing exosome support to reinforce long-term skin health.

DAILY Serum is best suited for those with moderate anti-aging, pigmentation, and tone or texture concerns. It's recommended for those seeking more gradual results, or for those interested in pre-juvenation and who wish to preserve, protect, and improve luminosity.
How often should I apply DAILY Serum?

( plated ) DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1-2 times daily, allowing the formula to fully absorb before layering additional skincare products.
Can I use DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) serums first to clean, product-free skin. And, let it sit for 5 minutes before applying other products.

The exosomes in our Renewosome® technology work most effectively with direct access to your skin. Once the DAILY Serum has dried, you'll know it has absorbed, and you can feel free to layer on any other products such as retinol, retinoid, vitamin C, moisturizer, sunscreen, etc. Don't forget your SPF!
Is DAILY Serum suitable for all skin types?

Yes. ( plated ) DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.
After having a skin procedure like laser, microneedling, or chemical peel and using ( plated ) CALM Serum post-procedure, is DAILY Serum best to transition to afterward?

Based on the recommendation of your provider, you may choose the ( plated ) DAILY Serum. However, you may wish to start with the ( plated ) INTENSE Serum and transition to the DAILY Serum to help maintain your results. Both serums will support your results.

The INTENSE Serum might be better suited for you if you are still struggling with wrinkles, fine lines, or stubborn pigmentation.
@platedskinscience