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( plated ) DAILY Serum Refill cartridge
( plated ) Skin Science 30 mL DAILY Refill Serum bottle, refill cartridge, and packaging with text that states 'DAILY Serum Refills are exclusively available for our upgraded packaging.
Video showing the DAILY Serum bottle and product.
Hands holding a value-size bottle of ( plated ) DAILY Serum, labeled '2x larger than INTENSE Serum'.
Scientific rendering of an exosome featuring the text 'Powered by Renewosome™ technology. Our platelet-derived Renewosome™ exosomes are the ultimate powerhouse, working to renew the look of your skin.'
( plated ) Skin Science DAILY Serum Refill cartridge and packaging, 30 mL / 1 fl oz
4.7
Rated 4.7 out of 5 stars
4.7 out of 5 Stars (279 Reviews)

Renewing Support for Youthful, Radiant Skin

DAILY Serum Refill

Sale price $244.00
30 mL Refill 30 mL Bottle

Visible transformation takes time. With each use, platelet-derived exosomes support your skin's natural renewal, driving results that build over time. Our refillable design helps you stay consistent, with $14 in savings built into every bottle.

MUST have the full-size DAILY Serum for the refill to work properly.

Size

30mL / 1 fl oz

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol

Instructions

Once or twice daily, begin your skincare routine with a gentle cleanser. Then, if desired, sweep a ( plated ) pad across your face and neck. Do not rinse.

Follow immediately with your ( plated ) serum. Allow 5 minutes before layering other products. With consistent use, results amplify over time.

Awards

Oprah Daily Editor's Choice 2023
( plated ) DAILY Serum Refill cartridge
DAILY Serum Refill Sale price $244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle

RENEW. REFILL. REPEAT.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!
Silver ( plated ) DAILY Serum bottle next to droplets of serum

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

EXOSOMES IN ACTION

Visibly Transformative Results

Skin Appears Visibly Calmer

Before: Side view of a person's lower face showing scattered blemishes, reddish spots, and uneven texture along the cheek and jawline.

Before

After: Side view of the same lower face showing the appearance of fewer visible blemishes and a smoother-looking cheek and jawline.

At 12 Weeks

Visibly Improved Skin Clarity

Before: Close-up of a woman's forehead and eye area showing visible skin texture, fine lines, and uneven tone.

Before

After: Close-up of the same forehead and eye area, showing the appearance of smoother-looking skin texture and a more even-looking tone.

At 12 Weeks

More Even-Looking Skin Tone

Before: Three-quarter view of a woman's face showing visible redness across the cheek, uneven skin tone, and skin texture.

Before

After: Three-quarter view of the same woman's face showing the appearance of reduced redness and a more even-looking complexion.

At 12 Weeks

WHERE BIOTECH MEETS BEAUTY™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

EXPLORE THE SCIENCE

See What They're saying

Customer Reviews

4.7
Rated 4.7 out of 5 stars
Based on 279 reviews
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279 reviews
  • Melissa G.
    Verified Buyer
    I recommend this product
    Age 30–39
    Rated 5 out of 5 stars
    11/2/26
    Great and works!

    Goes on smooth, clean, and non greasy. Saw improved skin texture and pigmentation

    Was this helpful?
  • CHRIS P.
    Verified Buyer
    I recommend this product
    Age 40–49
    Rated 5 out of 5 stars
    11/2/26
    Amazing Product!

    Have seen such amazing results since using the Plated Daily Serum.

    Was this helpful?
  • Brittany P.
    Verified Buyer
    I recommend this product
    Age 30–39
    Rated 5 out of 5 stars
    11/2/26
    Plated Daily

    Changed my skin completely. I will repurchase forever

    Was this helpful?
  • Sara J.
    Verified Buyer
    I recommend this product
    Age 50–59
    Rated 5 out of 5 stars
    11/2/26
    It works!

    Love this product after being away for 3 weeks and using it daily I had comments from coworkers when I got back who said it looks like I had less wrinkles then before I left!

    Was this helpful?
  • Jessica B.
    Verified Buyer
    I recommend this product
    Age 40–49
    Rated 4 out of 5 stars
    11/1/26
    genuinely love the product

    I’ve been using Plated Daily Serum for over two years, and I genuinely love the product. My skin looks and feels healthier overall. I’m giving it four stars because the dispenser didn’t work well with this refill, although I’ve never had that issue with previous refills. Otherwise, it’s a fantastic product!

    Was this helpful?
  • Jenna K.
    Verified Buyer
    I recommend this product
    Age 40–49
    Rated 5 out of 5 stars
    10/31/26
    It works

    Love this product, has done wonders for my sensitive skin

    Was this helpful?
  • JoEllen R.
    Verified Buyer
    I recommend this product
    Rated 4 out of 5 stars
    10/30/26
    Too early to tell

    But starting to see good improvement.

    Was this helpful?
  • Albert P.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/30/26
    INCREDIBLE

    MY FACE LOOKS INCREDIBLE; MY PLASTIC SURGEON RECOMMENDED THIS AFTER MY DEEP PLANE NECK LIFT

    ITS AN AMAZING DISCOVDERY!

    Was this helpful?
  • Marguerite G.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/30/26
    Better than most!

    Has helped with overall texture and redness

    Was this helpful?
  • Leslie V. B.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    10/29/26
    I'm Loving this serum!

    My first response to (plated) products was no, I cannot afford it! But I took the word of my functional doctor and bought it. I was nicely surprised with my results. My rosacea is much less than before and my skin looks much clearer. Even though I feel it is a bit drying, or maybe just doesn't have enough moisture in it for my particular skin, I've kept using it for half a year. Really stellar results.

    Was this helpful?
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DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum?

DAILY Serum is our deeply hydrating, platelet-derived exosome serum, known as the "glow" serum, powered by proprietary Renewosome® technology. This medical-grade formula infuses the skin with visible renewal for everyday radiance, applied once daily.

What does ( plated ) DAILY Serum do?

DAILY Serum deeply hydrates and infuses the skin with visible renewal to improve radiance. Clinically, it's been shown to reveal brighter skin, smooth the look of fine lines, and reduce the appearance of redness and dark spots, while helping defend against future signs of aging.

Who is ( plated ) DAILY Serum for?

DAILY Serum for anyone looking for daily anti-aging protection and a luminous glow. Its gentle, hydrating formula makes it an especially good fit for sensitive or barrier-compromised skin. As with all ( plated ) serums, your provider can help confirm it's the right match for your skin.

When should I use ( plated ) DAILY Serum?

DAILY Serum can be used in the morning and at night as the first step in your skincare routine.

How often should I apply ( plated ) DAILY Serum?

Once or twice daily, begin your skincare routine with a gentle cleanser. Then, if desired, sweep a ( plated ) pad across your face and neck. Do not rinse. Follow immediately with your ( plated ) serum. Allow 5 minutes before layering other products. With consistent use, results amplify over time.

Can I use ( plated ) DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) exosome serums first to clean, product-free skin.

Begin your skincare routine with a gentle cleanser. Then, if desired, sweep a ( plated ) pad across your face and neck. Do not rinse. Follow immediately with your ( plated ) serum. Allow 5 minutes before layering other products.

The platelet-derived exosomes in our Renewosome® technology work most effectively when they have direct access to your skin. After waiting 5 minutes, feel free to layer on any other products, such as retinol, retinoids, vitamin C, moisturizer, or sunscreen. Don't forget your SPF.

Is ( plated ) DAILY Serum suitable for all skin types?

Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.

After a skin procedure such as laser, microneedling, or a chemical peel, and after using ( plated ) CALM Serum post-procedure, is ( plated ) DAILY Serum the best to transition to afterward?

You may choose to stick to CALM Serum or transition to DAILY Serum (renewing support for a youthful glow) or INTENSE Serum (maximum exosome concentration for mature or stressed skin). Your provider can help you select the best choice for your skin goals.

 YOUR ROUTINE, REFINED 

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