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( plated ) DAILY Serum Refill cartridge
( plated ) Skin Science 30 mL DAILY Refill Serum bottle, refill cartridge, and packaging with text that states 'DAILY Serum Refills are exclusively available for our upgraded packaging.
Video showing the DAILY Serum bottle and product.
Hands holding a value-size bottle of ( plated ) DAILY Serum, labeled '2x larger than INTENSE Serum'.
Scientific rendering of an exosome featuring the text 'Powered by Renewosome™ technology. Our platelet-derived Renewosome™ exosomes are the ultimate powerhouse, working to renew the look of your skin.'
( plated ) Skin Science DAILY Serum Refill cartridge and packaging, 30 mL / 1 fl oz
4.7
Rated 4.7 out of 5 stars
242

Renewing Support for Youthful, Radiant Skin

DAILY Serum Refill

Sale price$244.00
30 mL Refill 30 mL Bottle

Visible transformation takes time. With each use, platelet-derived exosomes support your skin's natural renewal, driving results that build over time. Our refillable design helps you stay consistent, with $14 in savings built into every bottle.

MUST have the full-size DAILY Serum for the refill to work properly.

Size

30mL / 1 fl oz

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol

Instructions

Apply 1–2 times daily on clean, dry skin before any other skincare. Wait 5 minutes before layering additional products. Results amplify over time with consistent use.

Awards

Oprah Daily Editor's Choice 2023
( plated ) DAILY Serum Refill cartridge
DAILY Serum Refill Sale price$244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle

Renew. Refill. Repeat.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!
Silver ( plated ) DAILY Serum bottle next to droplets of serum

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

Exosomes in Action

Visibly Transformative Results

Skin Appears Visibly Calmer

Before

Before

At 12 Weeks

At 12 Weeks

Visibly Improved Skin Clarity

Before

Before

At 12 Weeks

At 12 Weeks

More Even-Looking Skin Tone

Before

Before

At 12 Weeks

At 12 Weeks

Where Biotech Meets Beauty™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

EXPLORE THE SCIENCE

See What They're saying

Customer Reviews

4.7
Rated 4.7 out of 5 stars
Based on 242 reviews
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242 reviews
  • Diane R.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/20/26
    Awesome product

    I love this product. It is really mellows out my rosacea. I have a subtle glow as well!

    Was this helpful?
  • Melanie M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/20/26
    Game changer

    This is the best stuff I have ever used. After turning 50 I worried about my skin. Wrinkles, aging. All that. Plated makes my skin glow.

    Was this helpful?
  • Jessica D.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/20/26
    Smart serum

    I am on my third refill now of this serum and love it. It has helped with the uneven skin texture and pigmentation sun damage.

    Was this helpful?
  • Krista S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/19/26
    Body serum

    Excellent

    Was this helpful?
  • Melissa M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/19/26
    The best!

    I love plated daily serum! I have very sensitive eczema proned skin and my skin cannot tolerate retinols so my dermatologist recommended Plated. My skin glows now! It’s my favorite product that makes the biggest difference in my skin!

    Was this helpful?
  • Emilia O.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/19/26
    AMAZING

    I’ve been on my journey to clear my skin since struggling with acne for YEARS. It’s still not completely gone but I can definitely see improvement! Would repurchase

    Was this helpful?
  • January C.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/19/26
    One of a kind

    From the first use i realized this was unlike anything id ever used. Very impressed with this product and how it makes my skin look and feel. The daily serum and the eye has become a staple in my regímen. I recommend to all of my friends!

    Was this helpful?
  • Susan I.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/19/26
    Wonderful product line

    These products are remarkable. I have heard great reviews on their hair thinning products as well.

    Was this helpful?
  • Danielle S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/16/26
    Love this !

    This product changed my skin so much, I’ve been using for a little over a year now, started on intense serum then switched to daily after 12ish months . My skin had a clear reduction in redness and just overall feels more glowing. If you are investing into in-office treatments I feel this serum has a strong ROI

    Was this helpful?
  • Marcia C.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    9/14/26
    Awesomeness

    This product is a little pricey but worth it! I’ve been using it for 2 months and will definitely continue. I’m 72 years old and played is gradually erasing my crepy arms and legs. Thank you for this wonderful product

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DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum?

DAILY Serum is our deeply hydrating, platelet-derived exosome serum, known as the "glow" serum, powered by proprietary Renewosome® technology. This medical-grade formula infuses the skin with visible renewal for everyday radiance, applied once daily.

What does ( plated ) DAILY Serum do?

DAILY Serum deeply hydrates and infuses the skin with visible renewal to improve radiance. Clinically, it's been shown to reveal brighter skin, smooth the look of fine lines, and reduce the appearance of redness and dark spots, while helping defend against future signs of aging.

Who is ( plated ) DAILY Serum for?

DAILY Serum for anyone looking for daily anti-aging protection and a luminous glow. Its gentle, hydrating formula makes it an especially good fit for sensitive or barrier-compromised skin. As with all ( plated ) serums, your provider can help confirm it's the right match for your skin.

When should I use ( plated ) DAILY Serum?

DAILY Serum can be used either in the morning or at night as the first step in your skincare routine.

How often should I apply ( plated ) DAILY Serum?

DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1–2 times daily. Wait 5 minutes before layering any other skincare product.

Can I use ( plated ) DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) exosome serums first to clean, product-free skin. And let it sit for 5 minutes before applying other products.

The platelet-derived exosomes in our Renewosome® technology work most effectively when they have direct access to your skin. After waiting 5 minutes, feel free to layer on any other products, such as retinol, retinoids, vitamin C, moisturizer, or sunscreen. Don't forget your SPF.

Is ( plated ) DAILY Serum suitable for all skin types?

Yes. DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.

After a skin procedure such as laser, microneedling, or a chemical peel, and after using ( plated ) CALM Serum post-procedure, is ( plated ) DAILY Serum the best to transition to afterward?

You may choose to stick to CALM Serum or transition to DAILY Serum (renewing support for a youthful glow) or INTENSE Serum (maximum exosome concentration for mature or stressed skin). Your provider can help you select the best choice for your skin goals.