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4.6
Rated 4.6 out of 5 stars
179

DAILY Serum Refill

Renewing Support for Youthful, Radiant Skin

Sale price$244.00

Visible transformation takes time. With each use, platelet-derived exosomes help support your skin’s natural renewal, driving results that continue to build long-term. Our refillable design keeps you consistent, with $14 savings built into every bottle.

Size: 30 mL / 1 fl oz

MUST have the full-size DAILY Serum for the refill to work properly.

Ingredients

Platelet-Derived Exosomes

Exosomes deliver signals that help skin renew and repair.

Glycerin

Gold standard humectant that locks in moisture to help balance and protect compromised skin.

Polyacrylate Crosspolymer-6

Helps nourish skin, while shielding the surface of the skin from environmental damage. (also known as - PAC6)

All Ingredients

water, glycerin, pentylene glycol, polyacrylate crosspolymer-6, Human Platelet Extract, caprylyl glycol, 1,2-hexanediol, arginine, hydrolyzed gelatin, silanetriol

Instructions

Apply 1–2 times daily on clean, dry skin before any other skincare. Wait 5 minutes before layering additional products. Results amplify over time with consistent use.

Awards

Oprah Daily Editor's Choice 2023

( plated ) DAILY Serum Refill cartridge
DAILY Serum Refill Sale price$244.00
Hand reaching towards a silver ( plated ) DAILY Serum skincare bottle

Renew. Refill. Repeat.

How to Refill

Step 1: Twist the bottom of the reusable pump to remove the empty cartridge.

Step 2: Unscrew the cap of the new refill cartridge, insert into the pump, and twist to secure.

Step 3: Close your empty cartridge and recycle. Enjoy your exosomes!

Silver ( plated ) DAILY Serum bottle next to droplets of serum

Patience Makes Perfect

Platelet-derived exosomes support your skin’s natural renewal process for results that build over time. In clinical studies, results continued to improve long-term, helping to:

  • Reveal brighter, more luminous skin 
  • Smooth the look of fine lines and wrinkles
  • Fight the look of redness and dark spots
  • Defends against future signs of aging

Exosome Science in Action

Visibly Transformative Results

Before-and-after comparison of a man's face showing visible skin barrier improvement over 12 weeks.
Before and after comparison of a person's face with visible skin texture changes over 12 weeks.
Before and after comparison of a person's face, showing visible improvement over 6 weeks.

Where Biotech Meets Beauty™

Discover the Power of Exosomes

Meet the most innovative topical ingredient in decades. Platelet-derived exosomes don’t mask the signs of aging; they reprogram the appearance of skin and hair. 

4.6
Rated 4.6 out of 5 stars
Based on 179 reviews
Total 5 star reviews: 140
Total 4 star reviews: 27
Total 3 star reviews: 4
Total 2 star reviews: 2
Total 1 star reviews: 6
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179 reviews
  • Patty H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    8/1/26
    My skin is more even toned

    Love how my skin looks over these past 2 weeks. I have been using the daily intense twice a day for about 7 weeks. I don’t mind paying a premium price when I see such results as this

  • Rachel G.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/31/26
    Game Changer!!

    Plated Daily has become one of those rare skincare products that I genuinely look forward to using every morning. From the very first application, I was impressed by how elegant the formula feels. It absorbs quickly, layers beautifully with the rest of my skincare, and leaves my skin feeling hydrated, comfortable, and balanced without any heaviness or residue.

    What I've come to appreciate most is how my skin looks over time. Rather than providing a temporary glow, Plated Daily has helped my complexion look consistently healthier, calmer, and more refined. My skin appears smoother, more even, and naturally radiant—the kind of healthy skin that doesn't need to be covered with heavy makeup.

    As someone who has invested in many luxury skincare products over the years, I can honestly say Plated Daily stands out because of its simplicity and performance. It doesn't try to do too much. Instead, it quietly supports healthier-looking skin day after day, and those cumulative results are what have impressed me the most.

    The formulation feels incredibly sophisticated, making it easy to use every day and effortless to incorporate into any routine. It has become a product I never want to be without.

    Plated has earned my trust through quality, thoughtful formulation, and visible results. Plated Daily is a perfect example of a product that delivers exactly what it promises, and it has become a permanent part of my skincare routine. I would confidently recommend it to anyone looking to…

  • Leeanna L.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/27/26
    Saving the environment and my skin!

    Really appreciate that there are refills available through plated. This company took the time to really think they’re packaging through. Matches with the thoughtfulness and research they put into this great product!

  • Worthy M.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/27/26
    Intense Serum

    I love this serum! It’s my go to!

  • Eileen O.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/25/26
    Daily

    I have been using over 3 years! Love it!

  • Tracy K.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/25/26
    Great product

    Good that you can refill and save $.

  • Elizabeth H.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/24/26
    Love this stuff

    My aging mantra.

    Botox

    Plated

    And acceptance .

    I’m thinking with plated products I won’t have to deal with the acceptance for a bit.

  • Jenny S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/24/26
    Daily serum

    This is the best serum I’ve ever used, and I’ve tried a lot. I have severe deep milia and rough uneven skin and the intense and daily serum has helped tremendously. Hands down best product out there!

  • Steven L.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/22/26
    An Exceptional Investment in Skin Longevity

    At 58, I have tried my fair share of anti-aging products that promised the world and delivered nothing. The (plated) Skin Science Daily Serum is the first product that actually made me stop and notice a real difference in the mirror. Years of outdoor activities left me with rough texture and dark spots. This serum has completely smoothed my skin and evened out my tone. I was starting to notice sagging around my jawline and cheeks. This has visibly firmed and tightened my skin, making it look much healthier. It absorbs instantly without leaving any greasy residue or shine, which I appreciate. My skin just feels resilient and hydrated all day. I wanted something easy. Just one pump in the morning after washing my face, and I'm done. The platelet-derived exosome technology in this bottle is the real deal. It is pricey, but it replaces three other steps in my old routine and actually works. If you are a guy looking to seriously clean up your skin and reverse some aging, this is worth every penny.

  • Sara S.
    Verified Buyer
    I recommend this product
    Rated 5 out of 5 stars
    7/21/26
    Can’t live without!!

    This has become my saving grace to my face!! Will never not have this in my routine

DAILY Serum Refill

Frequently Asked Questions

What is ( plated ) DAILY Serum designed to do?

Consumers affectionately nicknamed the ( plated ) DAILY Serum the “GLOW” serum.

DAILY Serum features a high concentration of hydrating ingredients and is formulated to help maintain visible improvements in skin tone, texture, and luminosity. Powered by proprietary Renewosome® technology, it delivers ongoing exosome support to reinforce long-term skin health.

DAILY Serum is best suited for those with moderate anti-aging, pigmentation, and tone or texture concerns. It's recommended for those seeking more gradual results, or for those interested in pre-juvenation and who wish to preserve, protect, and improve luminosity.

How often should I apply DAILY Serum?

( plated ) DAILY Serum is formulated for everyday use. Apply to clean, dry skin 1-2 times daily, allowing the formula to fully absorb before layering additional skincare products.

Can I use DAILY Serum with other skincare products?

Yes! For best results, always apply ( plated ) serums first to clean, product-free skin. And, let it sit for 5 minutes before applying other products.

The exosomes in our Renewosome® technology work most effectively with direct access to your skin. Once the DAILY Serum has dried, you'll know it has absorbed, and you can feel free to layer on any other products such as retinol, retinoid, vitamin C, moisturizer, sunscreen, etc. Don't forget your SPF!

Is DAILY Serum suitable for all skin types?

Yes. ( plated ) DAILY Serum is formulated to be gentle and hydrating, making it appropriate for all skin types, including sensitive skin.

After having a skin procedure like laser, microneedling, or chemical peel and using ( plated ) CALM Serum post-procedure, is DAILY Serum best to transition to afterward?

Based on the recommendation of your provider, you may choose the ( plated ) DAILY Serum. However, you may wish to start with the ( plated ) INTENSE Serum and transition to the DAILY Serum to help maintain your results. Both serums will support your results.

The INTENSE Serum might be better suited for you if you are still struggling with wrinkles, fine lines, or stubborn pigmentation.